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Publication in Scientific Journals (SCI or SCIE, Recent 3 years)
Kim WS, Kim JS, Kim HM, Kwon KW, Eum SY, Shin SJ, Comparison of immunogenicity and vaccine efficacy between
heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis, Scientific Reports,
2018, 8(1):14411
Shin SH, Jhun BW, Kim SY, Choe J, Jeon K, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Koh WJ, Nontuberculous
Mycobacterial Lung Diseases Caused by Mixed Infection with Mycobacterium avium Complex and Mycobacterium
abscessus Complex, Antimicrob Agents Chemother., 2018, 62(10). pii: e01105-18.
Kim WS, Shin MK, Shin SJ, MAP1981c, a Putative Nucleic Acid-Binding Protein, Produced by Mycobacterium avium
subsp. paratuberculosis, Induces Maturation of Dendritic Cells and Th1-Polarization, Front Cell Infect Microbiol.,
2018, 8:206.
Kim SY, Jhun BW, Moon SM, Shin SH, Jeon K, Kwon OJ, Yoo IY, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Suh GY,
Koh WJ, Mutations in gyrA and gyrB in Moxifloxacin-Resistant Mycobacterium avium Complex and Mycobacterium
abscessus Complex Clinical Isolates, Antimicrob Agents Chemother., 2018, 62(9). pii: e00527-18.
Choi SY, Kwon KW, Kim H, Choi HH, Shin SJ, Vaccine potential of ESAT-6 protein fused with consensus CD4+ T-cell
epitopes of PE/PPE proteins against highly pathogenic Mycobacterium tuberculosis strain HN878, Biochem Biophys Res
Commun., 2018,18;503(4):2195-2201.
Jhun BW, Kim SY, Moon SM, Jeon K, Kwon OJ, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Koh WJ, Development of
Macrolide Resistance and Reinfection in Refractory Mycobacterium avium Complex Lung Disease., Am J Respir Crit
Care Med. 2018 Jun 7.
Chae H, Shin SJ, Importance of differential identification of Mycobacterium tuberculosis strains for understanding
differences in their prevalence, treatment efficacy, and vaccine development, J Microbiol., 2018, 56(5):300-311.
Jhun BW, Yang B, Moon SM, Lee H, Park HY, Jeon K, Kwon OJ, Ahn J, Moon IJ, Shin SJ, Daley CL, Koh WJ, Amikacin
Inhalation as Salvage Therapy for Refractory Nontuberculous Mycobacterial Lung Disease, Antimicrob Agents
Chemother., 2018, 26;62(7). pii: e00011-18.
Kim WS, Jung ID, Kim JS, Kim HM, Kwon KW, Park YM, Shin SJ, Mycobacterium tuberculosis GrpE, A Heat-Shock
Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of
Dendritic Cells, Front Cell Infect Microbiol., 2018, 27;8:95.
Jang AR, Choi JH, Shin SJ, Park JH, Mycobacterium tuberculosis ESAT6 induces IFN-β gene expression in Macrophages
via TLRs-mediated signaling, Cytokine, 2018, 104:104-109.
Choi H, Jhun BW, Kim SY, Kim DH, Lee H, Jeon K, Kwon OJ, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Koh WJ,
Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease, Diagn Microbiol Infect Dis.,
2018, 90(4):293-295.
Jhun BW, Moon SM, Kim SY, Park HY, Jeon K, Kwon OJ, Huh HJ, Ki CS, Lee NY, Chung MJ, Lee KS, Shin SJ, Daley CL,
Koh WJ, Intermittent Antibiotic Therapy for Recurrent Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease,
Antimicrob Agents Chemother., 2018, 62(2). pii: e01812-17.
Kim WS, Kim JS, Shin MK, Shin SJ, A novel Th1-type T-cell immunity-biasing effect of malate dehydrogenase derived
from Mycobacterium avium subspecies paratuberculosis via the activation of dendritic cells, Cytokine, 2018, 104:14-22
Ko A, Wui SR, Ryu JI, Lee YJ, Hien DTT, Rhee I, Shin SJ, Park SA, Kim KS, Cho YJ, Lee NG, Potentiation of Th1-Type
Immune Responses to Mycobacterium tuberculosis Antigens in Mice by Cationic Liposomes Combined with
De-O-Acylated Lipooligosaccharide, J Microbiol Biotechnol., 2018, 28(1):136-144.
Song C, Phuengkham H, Kim S, Lee MS, Jeong JH, Shin SJ*, Lim YT*, Aminated nanomicelles as a designer vaccine
adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes, International Journal
of Nanomedicine, Accepted in September of 2017, (*Co-correspondence).
Lee JY, Lee MS, Kim DJ, Yang SJ, Lee SJ, Noh EJ, Shin SJ, Park JH, Nucleotide-Binding Oligomerization Domain 2
Contributes to Limiting Growth of Mycobacterium abscessus in the Lung of Mice by Regulating Cytokines and Nitric
Oxide Production, Front Immunol., 2017, 8:1477.
Choi H, Kim SY, Kim DH, Huh HJ, Ki CS, Lee NY, Lee SH, Shin S, Shin SJ, Daley CL, Koh WJ, Clinical Characteristics
and Treatment Outcomes of Patients with Acquired Macrolide-Resistant Mycobacterium abscessus Lung Disease,
Antimicrob Agents Chemother. 2017, 61(10). pii: e01146-17.
Koh WJ, Moon SM, Kim SY, Woo MA, Kim S, Jhun BW, Park HY, Jeon K, Huh HJ, Ki CS, Lee NY, Chung MJ, Lee KS,
Shin SJ, Daley CL, Kim H, Kwon OJ, Outcomes of Mycobacterium avium complex lung disease based on clinical
phenotype, Eur Respir J. 2017, 50(3). pii: 1602503.
Chae HS, Han SJ, Kim SY, Ki CS, Huh HJ, Yong D, Koh WJ, Shin SJ, Development of a one-step multiplex PCR assay for
differential detection of major Mycobacterium species, Journal of Clinical Microbiology, 2017, 55(9): 2736-2751
Kim SY, Shin SH, Moon SM, Yang B, Kim H, Kwon OJ, Huh HJ, Ki CS, Lee NY, Shin SJ*, Koh WJ, Distribution and
clinical significance of Mycobacterium avium complex species isolated from respiratory specimens, Diagn Microbiol
Infect Dis, 2017, 88(2):125-137. (*Co-correspondence).
Kim H, Kwon KW, Kim WS, Shin SJ. Virulence-dependent induction of interleukin-10-producing-tolerogenic dendritic
cells by Mycobacterium tuberculosis impedes optimal Th1 proliferation. Immunology, 2017, 15(12): 177-190
Jeong SH, Kim SY, Huh HJ, Ki CS, Lee NY, Kang CI, Chung DR, Peck KR, Shin SJ, Koh WJ, Mycobacteriological
characteristics and treatment outcomes in extrapulmonary Mycobacterium abscessus complex infections, Int J Infect Dis,
2017, 15;60:49-56
Kwon KW, Kim WS, Kim H, Han SJ, Hahn MY, Lee JS, Nam KT, Cho SN, Shin SJ. Novel vaccine potential of Rv3131,
a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K. Scientific
Reports, 2017, 8;7:44151
Kim SY, Koh WJ, Park HY, Jeon K, Lee SY, Yim JJ, Shin SJ. Down-Regulation of Serum High-Mobility Group Box 1
Protein in Patients with Pulmonary Tuberculosis and Nontuberculous Mycobacterial Lung disease, Tuberc Respir Dis,
2017, 80(2):153-158.
Jhun BW, Kim SY, Park HY, Jeon K, Shin SJ, Koh WJ, Changes in Serum IgA Antibody Levels against the
Glycopeptidolipid Core Antigen during Antibiotic Treatment of Mycobacterium avium Complex Lung Disease,
Jpn J Infect Dis. 2017 Mar 28
Choi HG, Choi S, Back YW, Paik S, Park HS, Kim WS, Kim H, Cha SB, Choi CH, Shin SJ*, Kim HJ*. Rv2299c, a novel
dendritic cell activating antigen of Mycobacterium tuberculosis, fused-ESAT-6 subunit vaccine confers improved and
durable protection against the hypervirulent strain HN878 in mice, Oncotarget, 2017, 21;8(12):19947-19967
(*Co-correspondence).
Hwang EH, Kim TH, Park JY, Hong JJ, Kim DH, Ha SJ, Yang SJ, Shin SJ*, Park JH*. TLR2 contributes to trigger immune
response of pleural mesothelial cells against Mycobacterium bovis BCG and M. tuberculosis infection. Cytokine.
2017, 25;95:80-87 (*Co-correspondence).
Yang B, Jhun BW, Moon SM, Lee H, Park HY, Jeon K, Kim DH, Kim SY, Shin SJ, Daley CL, Koh WJ,
Clofazimine-Containing Regimen for the Treatment of Mycobacterium abscessus Lung Disease, Antimicrob Agents
. 2017, 24;61(6). pii: e02052-16.
Groschel MI, Sayes F, Shin SJ, Frigui W, Pawlik A, Orgeur M, Canetti R, Honore N, Simeone R, van der Werf TS,
Bitter W, Cho SN, Majlessi L, Brosch, Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low
Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reprots. 2017, 14;18(11):2752-2765
Koh WJ, Jeong BH, Kim SY, Jeon K, Park KU, Jhun BW, Lee H, Park HY, Kim DH, Huh HJ, Ki CS, Lee NY, Kim HK,
Choi YS, Kim J, Lee SH, Kim CK, Shin SJ, Daley CL, Kim H, Kwon OJ, Mycobacterial Characteristics and Treatment
Outcomes in Mycobacterium abscessus Lung Disease, Clin Infect Dis. 2017, 1;64(3):309-316.
Choi H, Kim SY, Lee H, Jhun BW, Park HY, Jeon K, Kim DH, Huh HJ, Ki CS, Lee NY, Lee SH, Shin SJ, Daley CL, Koh WJ,
Clinical Characteristics and Treatment Outcomes of Patients with Macrolide-Resistant Mycobacterium massiliense
Lung Disease, Antimicrob Agents Chemother. 2017, 24;61(2). pii: e02189-16.
Jhun BW, Kim SY, Kong JH, Park JR, Park SY, Shim MA, Jeon K, Park HY, Shin SJ, Koh WJ, The 100 most-cited articles
on non-tuberculous mycobacterial infection from 1995 to 2015, Int J Tuberc Lung Dis. 2017, 1;21(1):100-106.
Kim SY, Chang B, Jeong BH, Park HY, Jeon K, Shin SJ*, Koh WJ*, Implication of vitamin D-associated factors in patients
with nontuberculous mycobacterial lung disease, Int J Tuberc Lung Dis, 2016, 20(12):1594-1602 (*Co-correspondence).
Lee BR, Jeong SK, Ahn BC, Lee BJ, Shin SJ*, Yum JS*, Ha SJ*, Combination of TLR1/2 and TLR3 ligands enhances
CD4+ T cell longevity and antibody responses by modulating type I IFN production. Scientific Reports, Scientific Reports,
2017, 1;6:32526 (*Co-correspondence).
Kim SY, Chang B, Jeong BH, Park HY, Jeon K, Shin SJ*, Koh WJ*, Implication of vitamin D-associated factors in
patients with nontuberculous mycobacterial lung disease, The International Journal of Tuberculosis and Lund Disease,
Accepted in August, 2016. (Co-correspondence)
Lee BR, Jeong SK, Ahn BC, Lee BJ, Shin SJ*, Yum JS*, Ha SJ*, Combination of TLR1/2 and TLR3 ligands enhances
CD4+ T cell longevity and antibody responses by modulating type I IFN production. Scientific Reports, Accepted in
August, 2016. (Co-correspondence)
Jeong BH, Jeon K, Park HY, Moon SM, Kim SY, Lee SY, Shin SJ, Daley CL, Koh WJ, Peak Plasma Concentration of
Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. Antimicrob Agents Chemother.
Accepted in August, 2016.
Choi R, Kim K, Kim MJ, Kim SY, Kwon OJ, Jeon K, Park HY, Jeong BH, Shin SJ, Koh WJ, Lee SY. Serum inflammatory
profiles in pulmonary tuberculosis and their association with treatment response. Journal of Proteomics, Accepted in
June, 2016.
Kim SY*, Shin SJ*, Jeong BH, Koh WJ, Successful antibiotic treatment of pulmonary disease caused by Mycobacterium
abscessus subsp. abscessus with C-to-T mutation at position 19 in erm(41) gene: case report. BMC Infect Dis.
2016, 17;16:207. (Co-first author)
Koh WJ, Jeong BH, Jeon K, Kim SY, Park KU, Park HY, Huh HJ, Ki CS, Lee NY, Lee SH, Kim CK, Daley CL, Shin SJ,
Kim H, Kwon OJ. Oral Macrolide Therapy Following Short-term Combination Antibiotic Treatment for Mycobacterium
massiliense Lung Disease. Chest. 2016, 7. pii: S0012-3692(16)48970-1.
Kim WS, Kim H, Kwon KW, Im SH, Lee BR, Ha SJ, Shin SJ. Cisplatin induces tolerogenic dendritic cells in response to
TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity. Oncotarget,
2016, 7(23): 33765-33782.
Kim WS, Kim JS, Cha SB, Kim M, Kwon KW, Kim SJ, Han SJ, Choi SY, Cho SN, Park JH, Shin SJ. Mycobacterium
tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine
potential against the hyper-virulent Beijing K strain, Oncotarget, 2016, 7(18): 24962-24982.
Cha SB, Kim WS, Kim JS, Kim HM, Kwon KW, Han SJ, Cho SN, Coler RN, Reed SG, Shin SJ. Pulmonary immunity and
durable protection induced by the ID93/GLA-SE vaccine candidate against the hyper-virulent Korean Beijing
Mycobacterium tuberculosis strain K, Vaccine, 2016, 34: 2179-2187.
Kim JS, Cha SH, Kim WS, Han SJ, Cha SB, Kim HM, Kwon KW, Kim SJ, Choi HH, Lee J, Cho SN, Koh WJ, Park YM,
Shin SJ. A Novel Therapeutic Approach using Menchymal Stem Cells to Protect against Mycobacterium abscessus.
Accepted in Stem Cells, 2016, 34(7): 1957-1970.
Kim SY, Jeong BH, Park HY, Jeon K, Han SJ, Shin SJ*, Koh WJ*. Association of ISMav6 with the Pattern of Antibiotic
Resistance in Korean Mycobacterium avium Clinical Isolates but No Relevance between Their Genotypes and Clinical
Features. PLoS One. 2016, 9;11(2):e0148917 (Co-correspondence).
Kim JS, Kim WS, Choi HH, Kim HM, Kwon KW, Han SJ, Cha SB, Cho SN, Koh WJ, Shin SJ. Mycobacterium tuberculosis
MmsA, a novel immunostimulatory antigen, induces dendritic cell activation and promotes Th1 cell-type immune responses.
Cell Immunol. 2015, 298(1-2):115-25.
Kim WS, Kim JS, Cha SB, Han SJ, Kim HM, Won KW, Kim SJ, Eum SY, Cho SN, Shin SJ, Virulence-dependent alterations
in the kinetics of immune cells during pulmonary infection by Mycobacterium tuberculosis, 2015, 16;10(12):e0145234.
Kim WS, Kim JS, Cha SB, Kim SJ, Kim HM, Kwon KW, Han SJ, Choi SY, Shin SJ. Mycobacterium tuberculosis PE27
activates dendritic cells and contributes to Th1-polarized memory immune responses during in vivo infection,
Immunobiology, 2016, 221(3): 440-53.
Lee JY, Hwang EH, Kim DJ, Oh SM, Lee KB, Shin SJ*, Park JH*, The role of nucleotide-binding oligomerization domain 1
during cytokine production by macrophages in response to Mycobacterium tuberculosis infection. Immunobiology.
2016, 221(1), 70-5 (Co-correspondence).
Cha SB, Kim WS, Kim JS, Kim H, Kwon KW, Han SJ, Eum SY, Cho SN, Shin SJ. Repeated Aerosolized-Boosting with
Gamma-Irradiated Mycobacterium bovis BCG Confers Improved Pulmonary Protection against the Hypervirulent
Mycobacterium tuberculosis Strain HN878 in Mice, PLoS One. 2015, 28;10(10):e0141577
Han SJ, Song T, Cho YJ, Kim JS, Choi SY, Bang HE, Chun J, Bai GH, Cho SN, Shin SJ. Complete genome sequence of
Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family. Standards in genomic
sciences, 2015, 14;10:78.
Kim SY, Park HY, Jeong BH, Jeon K, Huh HJ, Ki CS, Lee NY, Han SJ, Shin SJ*, Koh WJ*. Molecular analysis of clinical
isolates previously diagnosed as Mycobacterium intracellulare reveals incidental findings of "Mycobacterium indicus
pranii" genotypes in human lung infection. BMC Infect Dis. 2015, 30;15:406 (Co-correspondence).
Cha SB, Jeon BY, Kim WS, Kim JS, Kim HM, Kwon KW, Cho SN, Koh WJ, Shin SJ, Experimental Reactivation of
Pulmonary Mycobacterium avium Complex Infection in a Modified Cornell-Like Model. Plos One, 2015, 25;10(9):e0139251.
Lee JY, Hwang EH, Kim DJ, Oh SM, Lee KB, Shin SJ*, Park JH*, The role of nucleotide-binding oligomerization
domain 1 during cytokine production by macrophages in response to Mycobacterium tuberculosis infection.
Immunobiology. 2016, 221(1), 70-5 (Co-correspondence).
Lee JY, Hwang EH, Kim DJ, Oh SM, Lee KB, Shin SJ*, Park JH*, The role of nucleotide-binding oligomerization domain 1
during cytokine production by macrophages in response to Mycobacterium tuberculosis infection. Immunobiology.
2016, 221(1), 70-5 (Co-correspondence).
Choi HG, Kim WS, Back YW, Kim H, Kwon KW, Kim JS, Kim HJ, Shin SJ. Mycobacterium tuberculosis RpfE promotes
simultaneous Th1-and Th17-type T-cell immunity via TL4-dependent maturation of dendritic cells. European Journal of
Immunology, 2015, 45(7):1957-71.
Kim JS, Kang MJ, Kim WS, Han SJ, Kim HM, Kim HW, Kwon KW, Kim SJ, Cha SB, Eum SY, Koh WJ, Cho SN, Park JH,
Shin SJ. Essential Engagement of Toll-Like Receptor 2 in the Initiation of Early Protective Th1 Response against Rough
Variants of Mycobacterium abscessus. Infect Immune, 2015, 83(4): 1556-1567
Kim TH, Shin SJ, Park YM, Jung ID, Ryu SW, Kim DJ, Park JH, Park JH, Critical role of TRIF and MyD88 in
Mycobacterium tuberculosis Hsp70-mediated activation of dendritic cells. Cytokine, 2015, 71(2):139-44.
Synergistic effect of muramyl dipeptide with heat shock protein 70 from Mycobacterium tuberculosis on immune
activation. Kim TH, Park JH, Park YM, Ryu SW, Shin SJ, Park JH, Kim DJ, Immunobiology, 2015, 220(1):26-31.
Jeong YH, Hur YG, Lee H, Kim S, Cho JE, Chang J, Shin SJ, Lee H, Kang YA, Cho SN, Ha SJ. Discrimination between
Active and Latent Tuberculosis Based on Ratio of Antigen-Specific to Mitogen-Induced IP-10 Production.
J Clin Microbiol, 2015, 53(2):504-10.
Jang B, Kim HW, Kim JS, Kim WS, Lee BR, Kim S, Kim H, Han SJ, Ha SJ, Shin SJ. Peptidylarginine deiminase inhibition
impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T
cell-proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings. J Leukoc Biol,
2015 97(2):351-62.
Jeong BH, Jeon K, Park HY, Kim SY, Lee KS, Huh HJ, Ki CS, Lee NY, Shin SJ, Daley CL, Koh WJ, Intermittent
antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. Am J Respir Crit Care Med,
2015, 1;191(1):96-103
Kim SJ, Koh WJ, Kim YH, Jeong BH, Park HY, Jeon K, Kim JS, Cho SN, Shin SJ, Importance of reciprocal balance of
T cell immunity in Mycobacterium abscessus complex lung disease. PLoS One, 2014, 9(10): e109941.
Cha SB and Shin SJ, Mycobacterium bovis Bacillus Calmette-Guerin (BCG) and BCG-based Vaccines against
Tuberculosis. J Bacteriol Virol, 44(3): 1-8
Lee SJ*, Shin SJ*, Lee SJ, Lee MH, Kang TH, Noh KT, Shin YK, Kim HW, Yun CH, Jung ID, Park YM. Mycobacterium
abscessus MAB2560 induces maturation of dendritic cells via Toll-like receptor 4 and drives Th1 immune response.
BMB Rep. 2014, 47(9): 512-517 (*Equally contributed).
Kim SJ, Koh WJ, Kim YH, Jeong BH, Park HY, Jeon K, Kim JS, Cho SN, Shin SJ, Importance of reciprocal balance of T
cell immunity in Mycobacterium abscessus complex lung disease. Accepted in PLoS One (09/2014).
Cha SB, Shin SJ, Mycobacterium bovis Bacillus Calmette-Guerin (BCG) and BCG-based Vaccines Against Tuberculosis.
J Bacteriol Virol, 44(3): 1-8
Lee SJ*, Shin SJ*, Lee SJ, Lee MH, Kang TH, Noh KT, Shin YK, Kim HW, Yun CH, Jung ID, Park YM. Mycobacterium
abscessus MAB2560 induces maturation of dendritic cells via Toll-like receptor 4 and drives Th1 immune response.
BMB Rep. 2014 Mar 18. [Epub ahead of print] (*Equally contributed).
Lee SJ*, Shin SJ*, Lee MH*, Lee MG, Kang TH, Park WS, Soh BY, Park JH, Shin YK, Kim HW, Yun CH, Jung ID, Park YM.
A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor
immunotherapy, PLoS One, 2014, 7;9(8):e104351 (*Equally contributed).
Jung ID*, Shin SJ*, Lee MG, Kang TH, Han HD, Lee SJ, Kim WS, Kim HM, Park WS, Kim HW, Yun CH, Lee EK, Wu TC,
Park YM. Enhancement of Tumor-Specific T cell Mediated Immunity in Dendritic Cell-Based Vaccines by Mycobacterium
tuberculosis Heat-Shock Protein X, J Immunol, 2014, 1;193(3):1233-45 (*Equally contributed).
Lee J, Kim J, Lee J, Shin SJ, Shin EC. DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor
B elicits polyfunctional CD8(+) T cell responses. Clin Exp Vaccine Res. 2014, 3(2):235-43.
Yoo H, Jeon K, Kim SY, Jeong BH, Park HY, Ki CS, Lee NY, Shin SJ, Koh WJ. Clinical significance of Mycobacterium
szulgai isolates from respiratory specimens. Scand J Infect Dis. 2014, 46(3):169-74.
Kim SY, Koh WJ, Park HY, Jeon K, Kwon OJ, Cho SN, Shin SJ. Changes in serum immunomolecules during antibiotic
therapy for Mycobacterium avium complex lung disease. E-publication in Clin Exp Immunol. (Dec. 2013)
Jeong YH, Jeon BY, Gu SH, Cho SN, Shin SJ, Chang J, Ha SJ. Differentiation of antigen-specific T cells with limited
functional capacity during Mycobacterium tuberculosis infection. Infection and Immunity, 2014, 82(1):132-139.
Cho YJ, Yi H, Chun J, Cho SN, Charles LD, Koh WJ, Shin SJ. The Genome Sequence of ‘Mycobacterium massiliense’
Strain CIP 108297 Suggests the Independent Taxonomic Status of the Mycobacterium abscessus Complex at the
Subspecies level. PLOS ONE. 2013, 8(11):e81560.
Kim JS, Kim WS, Choi HG, Jang B, Lee K, Park JH, Kim HJ, Cho SN, Shin SJ. Mycobacterium tuberculosis RpfB drives
Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells. J Leukoc Biol. 2013, 94(4):733-49.
Jeong BH, Kim SY, Jeon K, Lee SY, Shin SJ, Koh WJ. Serodiagnosis of Mycobacterium avium Complex and
Mycobacterium abscessus Complex Pulmonary Disease by Use of IgA Antibodies to Glycopeptidolipid Core Antigen.
J ClinMicrobiol. 2013 Aug;51(8):2747-9.
Ko Y, Kim W, Shin BS, Yoo H, Eom JS, Lee JH, Jhun BW, Kim SY, Choi GE, Shin SJ, Koh WJ. Nontuberculous
Mycobacterial Lung Disease Caused by Mycobacterium chelonae: A Case Report. TubercRespir Dis (Seoul).
2013 Apr;74(4):191-4.
Jeong BH, Song JU, Kim W, Han SG, Ko Y, Song J, Chang B, Hong G, Kim SY, Choi GE, Shin SJ,
Koh WJ. Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium lentiflavum in a Patient with
Bronchiectasis. TubercRespir Dis (Seoul). 2013 Apr;74(4):187-90.
Jeon K, Kim SY, Jeong BH, Chang B, Shin SJ, Koh WJ. Severe vitamin D deficiency is associated with non-tuberculous
mycobacterial lung disease: A case-control study. Respirology. 2013 Aug;18(6):983-8.
Kim JS, Kim WS, Lee K, Won CJ, Kim JM, Eum SY, Koh WJ, Shin SJ. Differential immune responses to Segniliparus
rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles.
PLoS One. 2013, 8(3):e59646.
Shin SJ, Choi GE, Cho SN, Woo SY, Jeong BH, Jeon K, Koh WJ. Mycobacterial Genotypes Are Associated with
Clinical Manifestation and Progression of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium
massiliense. Clinical Infectious Diseases 2013, 57(1):32?39.
Koh WJ, Hong G, Kim SY, Jeong BH, Park HY, Jeon K, Kwon OJ, Lee SH, Kim CK, Shin SJ,Treatment of refractory
Mycobacterium avium complex lung disease with a moxifloxacin-containing regimen, Antimicrob Agents Chemother.
2013 Mar 11. [Epub ahead of print].
Shin AR, Lee KS, Lee KI, Shim TS, Koh WJ, Jeon HS, Son YJ, Shin SJ, Kim HJ. Serodiagnostic potential of Mycobacterium
avium MAV2054 and MAV5183 proteins.Clin Vaccine Immunol. 2013, 20(2):295-301.
Sim YS, Kim SY, Kim EJ, Shin SJ, KohWJ.Impaired Expression of MAPK Is Associated with the Downregulation of
TNF-α, IL-6, and IL-10 in Mycobacterium abscessus Lung Disease.TubercRespir Dis (Seoul). 2012, 72(3):275-83.
Byun EH, Kim WS, Kim JS, Won CJ, Choi HG, Kim HJ, Cho SN, Lee K, Zhang T, Hur GM, Shin SJ.Mycobacterium
paratuberculosisCobT activates dendritic cells via engagement of Toll-like receptor 4 resulting in Th1 cell expansion.
J Biol Chem. 2012, 287(46):38609-24.
Koh WJ, Jeong BH, Jeon K, Lee SY, Shin SJ.Therapeutic drug monitoring in the treatment of Mycobacterium avium
complex lung disease.Am J RespirCrit Care Med. 2012,186(8):797-802.
Yoo HS, Shin SJ.Recent research on bovine paratuberculosis in South Korea.Vet ImmunolImmunopathol. 2012,
148(1-2):23-8.
Koh WJ, Jeong BH, Jeon K, Lee NY, Lee KS, Woo SY, Shin SJ, Kwon OJ.Clinical significance of the differentiation
between Mycobacterium avium and Mycobacterium intracellulare in M avium complex lung disease.Chest.
2012, 142(6):1482-8.
Kim JJ, Lee HM, Shin DM, Kim W, Yuk JM, Jin HS, Lee SH, Cha GH, Kim JM, Lee ZW, Shin SJ, Yoo H, Park YK, Park JB,
Chung J, Yoshimori T, Jo EK.Host cell autophagy activated by antibiotics is required for their effective antimycobacterial
drug action.Cell Host Microbe. 2012, 11(5):457-68.
Choi GE, Min KN, Won CJ, Jeon K, Shin SJ, Koh WJ.Activities of moxifloxacin in combination with macrolides against
clinical isolates of Mycobacterium abscessus and Mycobacterium massiliense.Antimicrob Agents Chemother.
2012, 56(7):3549-55.
Choi GE, Cho YJ, Koh WJ, Chun J, Cho SN, Shin SJ.Draft genome sequence of Mycobacterium abscessus subsp.
bolletiiBD(T).J Bacteriol. 2012, 194(10):2756-7.
Byun EH, Kim WS, Kim JS, Jung ID, Park YM, Kim HJ, Cho SN, Shin SJ.Mycobacterium tuberculosis Rv0577, a novel TLR2
agonist, induces maturation of dendritic cells and drives Th1 immune response.FASEB J. 2012, 26(6):2695-711.
Kim K, Sohn H, Kim JS, Choi HG, Byun EH, Lee KI, Shin SJ, Song CH, Park JK, Kim HJ.Mycobacterium tuberculosis
Rv0652 stimulates production of tumour necrosis factor and monocytes chemoattractant protein-1 in macrophages through
the Toll-like receptor 4 pathway.Immunology. 2012, 136(2):231-40.
Jung ID, Kim HY, Park JW, Lee CM, Noh KT, Kang HK, Heo DR, Lee SJ, Son KH, Park HJ, Shin SJ, Park JH, Ryu SW,
Park YM.RG-II from Panax ginseng C.A. Meyer suppresses asthmatic reaction.BMB Rep. 2012, 45(2):79-84.
Byun EH, Kim WS, Shin AR, Kim JS, Whang J, Won CJ, Choi Y, Kim SY, Koh WJ, Kim HJ, Shin SJ.Rv0315, a novel
immunostimulatory antigen of Mycobacterium tuberculosis, activates dendritic cells and drives Th1 immune responses.
J Mol Med (Berl). 2012, 90(3):285-98.
Noh KT, Shin SJ, Son KH, Jung ID, Kang HK, Lee SJ, Lee EK, Shin YK, You JC, Park YM.The Mycobacterium avium
subsp. paratuberculosisfibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based
cancer vaccine potency.ExpMol Med. 2012, 31;44(5):340-9.
Kim JS,Ryu MJ, Byun EH, Kim WS, Whang J, Min KN, Shong M, Kim HJ, Shin SJ. Differential immune response of
adipocytes to virulent and attenuated Mycobacterium tuberculosis. Microbes and Infection. 2011, 13(14-15):1242-1251
Koh WJ, Choi GE, Lee SH, Park YK, Lee NY, Shin SJ. First Case of Segniliparusrotundus Pneumonia in a Patient with
Bronchiectasis. Journal of Clinical Microbiology. 2011, 49(9):3403-3405
Shin SJ, Heoa DR, Kim WS, Noh KT, Park JW, Son KH, Park WS, Lee MG, Kim DJ, Shin YK, Jung ID, Park YM.
Mycobacterium tuberculosis lpdC, Rv0462, induces dendritic cell maturation and Th1 polarization. Biochemical and
Biophysical ResearchCommunications. 2011, 411(3):642-647
Kim SY, Sohn HS, Choi GE, Cho SN, Oh TW, Kim HJ, Whang J, Kim JS, Byun EH, Kim WS, Min KN, Kim JM, Shin SJ.
Conversion of Mycobacterium smegmatis to a pathogenic phenotype via passage of epithelial cells during
macrophageinfection. Medical Microbiology and Immunology. 2011, 200(3):177-191.
Whang J, Lee BS, Choi GE, Cho SN, Kil PY, Collins MT and Shin SJ. PCR restriction fragment length polymorphism
of the rpoB gene for identification of Mycobacterium avium subsp. paratuberculosis and differentiation of Mycobacterium
aviumsubspecies. Diagnostic Microbiology and Infectious Disease. 2011, 70(1): 65-71.
Jung ID, Jeong SK, Lee CM, Noh KT, Heo DR, Shin YK, Yun CH, Koh WJ, Akira S, Whang J, Kim HJ, Park WS, Park YM,
Shin SJ
. Enhanced efficacy of therapeutic cancer vaccines produced by co-treatment with Mycobacterium tuberculosis
heparin- binding hemagglutinin, a novel TLR4 agonist. Cancer Research. 2011, 71(8):2858-2870.
Choi GE, Chang CL, Whang J, Kim HJ, Kwon OJ, Koh WJ, Shin SJ. Efficient differentiation of Mycobacterium
abscessuscomplex to the species level by a novel PCR-based variable-number tandem-repeat assay. Journal of Clinical
Microbiology. 2011, 49(3):1107-1109.
Koh WJ, Jeon KM, Lee NY, Kim BJ, Kook YH, Lee SH, Park YK, Kim CK, Shin SJ, Huitt GA, Daley CL, Kwon OJ, Clinical
Significance of Differentiation between Mycobacterium abscessus and Mycobacterium massiliense: Mycobacterium
massiliense Lung Disease Has a Better Prognosis than Mycobacterium abscessus Lung Disease, American journal
ofrespiratory and critical care medicine. 2011, 183(3):405-410.
Shin SJ, Lee BS, Koh WJ, Manning EJ, Anklam K, Sreevatsan S, Lambrecht RS, Collins MT., Efficient differentiation of
Mycobacterium avium complex species and subspecies by use of five-target multiplex PCR. J ClinMicrobiol. 2010,
48(11):4057-4062.
Shin AR, Sohn H, Won CJ, Lee B, Kim WS, Kang HB, Kim HJ, Cho SN, Shin SJ, Characterization and identification of
distinct Mycobacterium massiliense extracellular proteins from those of Mycobacterium abscessus. Journal of Microbiology,
2010, 48(4):502-511.
Cho D, Shin SJ, Collins MT., B-CELL epitope specificity of carboxy terminus of Mycobacterium paratuberculosisModD,
J Immunoassay Immunochem 2010, 31(3):181-192
Sohn H, Kim KW, Kang HB, Won CJ, Kim WS, Lee B, Kwon OJ, Koh WJ, Shin SJ, Kim HJ., Induction of macrophage death
by clinical strains of Mycobacterium kansasii, Microbial Pathogenesis., 2010, 48(5): 160-167.
Choi GE, Eom SH, Jung KH, Son JW, Shin AR, Shin SJ, Kim KH, Chang CL, Kim HJ., CysA2: A candidate
erodiagnosticmarker for Mycobacterium tuberculosis infection.., Respirology. 2010, 15(4): 636-642.
Go-Eun Choi, Yong-Joon Cho, Won-Jung Koh, Jongsik Chun, Sang-Nae Cho, and Sung Jae Shin, Draft Genome
Sequence of Mycobacterium abscessus subsp. bolletii BDT, Accepted in Journal of Bacteriology (2012. 03. 08)
Eui-Hong Byun, Woo Sik Kim, Jong-Seok Kim, In Duk Jung, Yeong-Min Park, Hwa-Jung Kim, Sang-Nae Cho,
and Sung Jae Shin , Mycobacterium tuberculosis Rv0577, a Novel TLR2 Agonist, Induces Maturation of Dendritic cells
and Drives Th1 Immune Response, Accepted in FASEB Journal (2012. 03. 01)
Kim K, Sohn H, Kim JS, Choi HG, Byun EH, Lee KI, Shin SJ, Song CH, Park JK, Kim HJ., Mycobacterium tuberculosis
Rv0652 stimulates production of TNF and MCP-1 in macrophages through the TLR4 pathway., Immunology. 2012 Feb 20.
doi: 10.1111/j.1365-2567.2012.03575.x. [Epub ahead of print]
Byun EH, Kim WS, Shin AR, Kim JS, Whang J, Won CJ, Choi Y, Kim SY, Koh WJ, Kim HJ, Shin SJ., Rv0315, a novel
immunostimulatory antigen of Mycobacterium tuberculosis, activates dendritic cells and drives Th1 immune responses.
Journal of Molecular Medicine. 2012. 90 (3): 285-298
Noh KT, Shin SJ, Son KH, Jung ID, Kang HK, Lee SJ, Lee EK, Shin YK, You JC, Park YM. The Mycobacterium avium
subsp. paratuberculosis fibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based cancer
vaccine potency., Exp Mol Med. 2012 Feb 9. [Epub ahead of print]
Sohn H, Kim JS, Shin SJ, Kim K, Won CJ, Kim WS, Min KN, Choi HG, Lee JC, Park JK, Kim HJ., Targeting of Mycobacterium
tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages. PLoS Pathog. 2011. 7(12):e1002435.
Yong HY, Choi GE, Lee BS, M.S., Whang J, Shin SJ. Disseminated infection due to Mycobacterium avium subsp. avium
in an Asian elephant (Elephas maximus). Journal of Zoo and Wildlife Medicine. 2011. 42(4):743-746
Kim JS, Ryu MJ, Byun EH, Kim WS, Whang J, Min KN, Shong M, Kim HJ, Shin SJ. Differential immune response of
adipocytes to virulent and attenuated Mycobacterium tuberculosis. Microbes and Infection. 2011. 13(14-15):1242-1251
Koh WJ, Choi GE, Lee SH, Park YK, Lee NY, Shin SJ. First Case of Segniliparus rotundus Pneumonia in a Patient with
Bronchiectasis. Journal of Clinical Microbiology. 2011. 49(9):3403-3405
Shin SJ, Heoa DR, Kim WS, Noh KT, Park JW, Son KH, Park WS, Lee MG, Kim DJ, Shin YK, Jung ID, Park YM.
Mycobacterium tuberculosis lpdC, Rv0462, induces dendritic cell maturation and Th1 polarization. Biochemical and
Biophysical Research Communications. 2011. 411(3):642-647
Kim SY, Sohn HS, Choi GE, Cho SN, Oh TW, Kim HJ, Whang J, Kim JS, Byun EH, Kim WS, Min KN, Kim JM, Shin SJ,
Conversion of Mycobacterium smegmatis to a pathogenic phenotype via passage of epithelial cells during macrophage
infection. Medical Microbiology and Immunology. 2011. 200(3):177-191.
Whang J, Lee BS, Choi GE, Cho SN, Kil PY, Collins MT and Shin SJ. PCR restriction fragment length polymorphism of the
rpoB gene for identification of Mycobacterium avium subsp. paratuberculosis and differentiation of Mycobacterium avium
subspecies. Diagnostic Microbiology and Infectious Disease. 2011. 70(1): 65-71.
Jung ID, Jeong SK, Lee CM, Noh KT, Heo DR, Shin YK, Yun CH, Koh WJ, Akira S, Whang J, Kim HJ, Park WS, Park YM,
Shin SJ
. Enhanced efficacy of therapeutic cancer vaccines produced by co-treatment with Mycobacterium tuberculosis
heparin- binding hemagglutinin, a novel TLR4 agonist. Cancer Research. 2011. 71(8):2858-2870.
Choi GE, Chang CL, Whang J, Kim HJ, Kwon OJ, Koh WJ, Shin SJ. Efficient differentiation of Mycobacterium abscessus
complex to the species level by a novel PCR-based variable-number tandem-repeat assay. Journal of Clinical Microbiology.
2011. 49(3):1107-1109.
Koh WJ, Jeon KM, Lee NY, Kim BJ, Kook YH, Lee SH, Park YK, Kim CK, Shin SJ, Huitt GA, Daley CL, Kwon OJ, Clinical
Significance of Differentiation between Mycobacterium abscessus and Mycobacterium massiliense: Mycobacterium
massiliense Lung Disease Has a Better Prognosis than Mycobacterium abscessus Lung Disease, American journal of
respiratory and critical care medicine. 2011. 183(3):405-410.
Shin SJ, Lee BS, Koh WJ, Manning EJ, Anklam K, Sreevatsan S, Lambrecht RS, Collins MT., Efficient differentiation of
Mycobacterium avium complex species and subspecies by use of five-target multiplex PCR. J Clin Microbiol. 2010.
48(11):4057-4062.
Shin AR, Sohn H, Won CJ, Lee B, Kim WS, Kang HB, Kim HJ, Cho SN, Shin SJ., Characterization and identification of
distinct Mycobacterium massiliense extracellular proteins from those of Mycobacterium abscessus. Journal of Microbiology,
2010. 48(4):502-511.
Cho D, Shin SJ, Collins MT., B-CELL epitope specificity of carboxy terminus of Mycobacterium paratuberculosis ModD.,
J Immunoassay Immunochem 2010. 31(3):181-192
Sohn H, Kim KW, Kang HB, Won CJ, Kim WS, Lee B, Kwon OJ, Koh WJ, Shin SJ, Kim HJ., Induction of macrophage death
by clinical strains of Mycobacterium kansasii., Microbial Pathogenesis., 2010. 48(5): 160-167.
Choi GE, Eom SH, Jung KH, Son JW, Shin AR, Shin SJ, Kim KH, Chang CL, Kim HJ., CysA2: A candidate serodiagnostic
marker for Mycobacterium tuberculosis infection.., Respirology. 2010. 15(4): 636-642.
Shin AR, Kim HJ, Cho SN, Collins MT, Manning EJ, Naser SA, Shin SJ. Identification of sero-reactive proteins in culture
filtrate antigen of Mycobacterium avium subsp paratuberculosis human isolates to sera from Crohn’s disease patients.
FEMS Immunology and Medical Microbiology, 2010. 58(1):128-137.
Sohn HS, Kim HJ, Kim JM, Kwon OJ, Koh WJ, Shin SJ. High virulent clinical isolates of Mycobacterium abscessus from
patients with the upper lobe fibrocavitary form of pulmonary disease. Microbial Pathogenesis. 2009. 47(6):321-328.
Kim SY, Shin AR, Kim HJ, Cho SN, Park JK, Shin SJ., Identification of Rv2041c, a novel immunogenic antigen from
Mycobacterium tuberculosis with serodiagnostic potential. Scandinavian Journal of Immunology. 2009. 70(5):457-464.
Jeon BY, Kwak JY, Lee SS, Cho SN, Won CJ, Kim JM, Shin SJ., Comparative analysis of immune responses to
Mycobacterium abscessus infection and its antigens in two murine models, Journal of Microbiology, 2009. 47(5):633-640
Shin SJ, Lee SS, Manning EJ, Collins MT. Production of and applications for a polyclonal IgY diagnostic reagent specific
for Mycobacterium avium subsp. paratuberculosis. Journal of Microbiology, 2009. 47(5):600-609
Shin SJ, Lee JS, Collins MT, Jung ID, Jeong YI, Lee CM, Shin YK, Kim D, Park YM. Mycobacterium avium subsp.
paratuberculosis fibronectin attachment protein activates dendritic cells and induces a Th1 polarization. Infect Immun.
2009. 77(7):2979-288.
Shin SJ, Anklam K, Manning EJ, Collins MT., A rapid mycobacterial liquid culture screening method for Mycobacterium
avium complex based on secreted antigen-capture ELISA, Clin Vaccine Immunol, 2009. 16(5):613-620
Kim SY, Shin SJ, Song CH, Jo EK, Kim HJ, Park JK., Destruction of Bacillus licheniformis spores by microwave irradiation,
J Appl Microbiol. 2009.03. 106(3):877-885.
Sohn H., Shin SJ, Lee KS, Kim SY, Shin DM, Jo EK, Park JK, Kim HJ, Induction of cell death in human macrophages by a
highly virulent Korean isolate of Mycobacterium tuberculosis and the virulent strain H37Rv, Scandinavian journal of
immunology, 2009. 69, 43-50.
Shin AR, Lee SS, Lee BS, Cho SN, Kim HJ, Shin SJ, Improved diagnostic sensitivity using a cocktail-ELISA containing the
abundantly expressed antigens of M. tuberculosis K-strain in Korean patients. Clin Vaccine Immunol. 2008. 15(12):1788-1795.
Kim SY, Park JK, Cho SN, Kim HJ, Lee BS, Shin SJ, Differentially expressed genes in Mycobacterium tuberculosis H37Rv
under mild acidic and hypoxic conditions. Journal of Medical Microbiology, 2008. 57(Pt 12):1473-1480
Shin DM, Yang CS, Yuk JM, Lee JY, Kim KH, Shin SJ, Takahara K, Lee SJ, Jo EK. Mycobacterium abscessus activates
the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1.
Cell Microbiol. 2008. 10(8):1608-1621
Shin SJ, Cho D, Collins MT., Novel enzyme-linked immunosorbent assay for bovine paratuberculosis based on early
secreted antigens of Mycobacterium avium subsp. paratuberculosis. Clin Vaccine Immunol. 2008. 15(8):1277-1281.
Kim SY, Song CH, Jo EK, Kim HJ, Park JK, Shin SJ. Identification of novel metronidazole-inducible genes in Mycobacterium
smegmatis using a customized amplification library. FEMS Microbiol Lett. 2008. 282(2):282-289.
Sohn H, Lee KS, Ko YK, Ryu JW, Woo JC, Koo DW, Shin SJ, Ahn SJ, Shin AR, Song CH, Jo EK, Park JK, Kim HJ. In vitro
and ex vivo activity of new derivatives of acetohydroxyacid synthase inhibitors against Mycobacterium tuberculosis and
non- tuberculous mycobacteria. Int J Antimicrob Agents. 2008. 31(6):567-571
Shin SJ, Collins MT. Thiopurine drugs (azathioprine and 6-mercaptopurine) inhibit Mycobacterium paratuberculosis
growth in vitro. Antimicrob Agents Chemother. 2008. 52(2): 418-426.


Publication in Scientific Journals (Domestic, Recent 3 years)
Go-Eun Choi, Youngsuk Jo and Sung Jae Shin, Current understanding of Mycobacterium abscessus infection. Accepted in
Journal of Bacteriology and Virology (2012. 03. 02)
Kwon YM, Jung KH, Choi GE, Shin AR, Lee BS, Won CJ, Kim WS, Shin SJ, Paerk JK, Chang CL, Kim HJ, Identification and
Diagnostic Utility of Serologic Reactive Antigens from Mycobacterium tuberculosis Sonic Extracts. Journal of Bacteriology
and Virology. 2011.39(4). 329-336
Kim SY, Shin AR, Lee BS, Kim HJ, Jeon BY, Cho SN, Park JK, and Shin SJ. Characterization of Immune Responses to
Mycobacterium tuberculosis Rv2041c protein. Journal of Bacteriology and Virology. 2009. 39(3): 183-193.
Lee KS, Sohn H., Lee SS, Lee BS, Kim HJ, Shin SJ, Cytokine profiles of macrophages by Mycobacterium abscessus
conditional morphotype variants and comparison of their extracellular-protein expressions, Journal of Bacteriology and
Virology, 2008. 38(3), 109-118
Cho DH, PhD, Hwang HE, PhD, Park JI, MD, Shin SJ, PhD, Lee JY, MA, Jeon BH, MD, PhD, Kim HJ, MD, PhD, Lee YH,
MD, PhD, Park JK, MD, PhD, Lee JU, MD, PhD. An Analysis of the Education Environment of a High School Life Science
Class in Daejeon for the Development of a Bio-medical Science Experience Program. Korean education for medicine.
2007. 19(4): 287- 294.


특허
Pharmaceutical composition for prevention or treatment of tuberculosis containing mesenchymal stem cells,
10-2015-0045622, 2015. 03. 31
Vaccine composition for tuberculosis containing Rv3131 protein, 10-2015-0050958, 2015. 04. 10
Animal model forming necrotic granuloma for study of tuberculosis and method for producing the same,
10-2015-0055952, 2015. 04. 21
Biomarkers composition for diagnosis of Mycobacterium abscessus complex lung disease, Shin SJ, Koh WJ, Kim SY,
Patent application no. 10-2014-0117831 (09/04/2014)
Vaccine composition for tuberculosis containing Rv3112 protein, Shin SJ, Kim WS, Cho SN, Han SJ, Patent application no.
10-2014-0093510 (07/23/2014)
Vaccine composition for tuberculosis containing MTBK 20620 or MTBK 24820 protein, Shin SJ, Kim WS, Cho SN, Han SJ,
Patent application no. 10-2014-0093499 (07/23/2014)
Composition comprising ADK for preventing or treating sepsis or septic shock, Park YM, Jung ID, Shin SJ, Park JH,
Lee SJ, Patent application no. 10-2014-0048573 (04/23/2014)
COMPOSITION FOR ENHANCING PROTECTIVE EFFICATY OF VACCINE AGAINST TUBERCULOSIS AND THE METHOD
THEREOF, Shin SJ, Kim JS, Kim WS, Cho SN, Patent application no. 10-2014-0027341 (03/07/2014)
Vaccine composition for tuberculosis containing Rv0351 protein, Shin SJ, Kim JS, Kim WS, Cho SN, Han SJ, Patent
application no. 10-2014-0023165 (02/27/2014)
Animal model for the study of granuloma and method for producing the same, Shin SJ, Kim JS, Patent application no.
10-2013-0113197 (09/24/2013)
Composition for inducing maturation of dendritic cell comprising Mycobacterium abscessus MAB1843, Shin SJ,
Park YM, Jung ID, Kim JS, Kim WS, Patent application no. 10-2013-0113193 (09/24/2013)
Compositon for inducing maturation of dendritic cell comprising MAB2560, Park YM, Jung ID, Shin SJ, Patent application no.
10-2013-0014324 (02/08/2013)
Compositon for maturating dendritic cell comprising Mycobacterium tuberculosis Rv2769c, Cho SN, Lee HJ, Shin SJ,
Byun EH, Kim WS, Kim JS, Patent application no. 10-2012-0041665 (04/20/2012)
Compositon for maturating dendritic cell comprising Mycobaccterium paratuberculosis MAP1981c, Shin SJ, Cho SN, Byun EH, Kim WS, Kim JS, Patent application no. 10-2012-0041654 (04/20/2012)
Compositon for inducing maturation of dendritic cell comprising Mycobacterium tuberculosis RpfB, Cho SN, Lee HJ,
Shin SJ, Choi HG, Byun EH, Kim WS, Kim JS, Kim HJ, Patent application no. 10-2012-0013868 (02/10/2012)
COMPOSITION FOR MATURATION OF DENDRITIC CELL COMPRISING Mycobacterium paratuberculosis MAP1305, Park YM,
Jung ID, Shin SJ, Kim WS, Patent application no. 10-2012-0012760 (02/08/2012)
COMPOSITION FOR MATURATION OF DENDRITIC CELL COMPRISING Mycobacterium tuberculosis Rv2005c, Park YM,
Jung ID, Shin SJ, Kim WS, Patent application no. 10-2012-0012297 (02/07/2012)
Maturation method for Dendritic cell using Mycobacterium tuberculosis Rv2299c, Shin SJ, Choi HG, Byun EH, Kim WS,
Kim JS, Kim HJ, Patent application no. 10-2011-0103498 (10/11/2011), Patent registration no. 10-1270999 (05/29/2013)
Method for transformation of Mycobacteria by the modified heat shock protocol with lysozyme, Shin SJ, Whang J, Kim HJ,
Patent application no. 10-2011-0102388 (10/07/2011), Patent registration no. 10-1237255 (02/20/2013)
Maturation method for Dendritic cell using Mycobacterium paratuberculosis MAP1948, Shin SJ, Byun EH, Kim WS, Kim JS,
Kim HJ, Patent application no. 10-2011-0102394 (10/07/2011), Patent registration no. 10-1270997 (05/29/2013)
Compositions for diagnosis of M. abscessus infection, Shin SJ, Kim HJ, Shin AR, Oh JH, Patent application no.
10-2011-0095102 (09/21/2011), Patent registration no. 10-1082816 (11/07/2011)
Maturation method for Dendritic cell using M.tuberculosis Rv0577, Shin SJ, Kim HJ, Byun EH, Kim WS, Kim, Jong Seok,
Patent application no. 10-2011-0073680 (07/25/2011), Patent registration no. 10-1264821 (05/09/2013)
Maturation method for Dendritic cell using Mycobacterium abscessus MAB0981c, Shin SJ, Kim HJ, Byun EH, Kim WS,
Shin AR, Patent application no. 10-2011-0047697 (05/20/2011), Patent registration no. 10-1264811 (05/09/2013)
Maturation method for Dendritic cell using M.tuberculosis Rv0315, Shin SJ, Kim HJ, Byun EH, Kim WS, Patent application no.
10-2011-0021906 (03/11/2011), Patent registration no. 10-1244245 (03/11/2013)
Dendritic cell based cancer medicine using M. tuberculosis Rv0652 protein as an adjuvant, Shin SJ, Jung ID, Park YM,
Kim HJ, Patent application no. 10-2011-0010165 (02/01/2012), Patent registration no. 10-1290230 (07/22/2013)
Vaccine for preventing and treating inflammatory bowel disease comprising Mycobacterium paratuberculosis, Shin SJ,
Min KN, Won CJ, Kim WS, Patent application no. 10-2011-0003830 (01/14/2011), Patent registration no.
10-1296846 (08/08/2013)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003719 (01/13/2011), Patent registration no. 10-1105168 (01/05/2012)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003716 (01/13/2011), Patent registration no. 10-1105163 (01/05/2012)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2011-0003713 (01/13/2011), Patent registration no. 10-1105156 (01/05/2012)
A composition for maturation of Dendritic cell containing HspⅩ, Park YM, Jung ID, Shin SJ, Kim HJ, Patent application no.
10-2010-0106773 (10/29/2010), Patent registration no. 10-1172874 (08/03/2012)
A composition for maturation of dendritic cell containing M. tuberculosis RV0351 protein, Shin SJ, Park YM, Jung ID,
Kim HJ, Kim WS, Patent application no. 10-2010-0098571 (10/11/2010), Patent registration no. 10-1221590 (01/07/2013)
Maturation method using M. tuberculosis RV0652 protein for Dendritic cell, Park YM, Jung ID, Shin SJ, Kim HJ, Patent
application no. 10-2010-0046354 (05/18/2010), Patent registration no. 10-1087033 (11/21/2011)
Biomarkers for the serodiagnosis of serodiagnosis of diagnosis of extrapulmonary tuberculosis, Shin SJ, Kim HJ, Shin AR,
Cho SN, Patent application no. 10-2010-0026799 (03/25/2010), Patent registration no. 10-1251041 (03/29/2013)
Dendritic cell based cancer medicine using HBHA as an adjuvant, Park YM, Jung ID, Shin SJ, Kim HJ, Patent application no.
10-2010-0009750 (02/02/2010), Patent registration no. 10-1209416 (11/30/2012)
Maturation method for Dendritic cell using heparin-binding hemagglutin, Park YM, Jung ID, Shin SJ, Kim HJ, Patent
application no. 10-2010-0009747 (02/02/2010), Patent registration no. 10-1052350 (07/21/2011)
Primer pairs for diagnosis of Mycobacterium avium complex and Usage Thereof, Shin SJ, Lee BS, Michael T. Collins
Elizabeth J.B. Manning, Patent application no. 10-2009-0099328 (10/19/2009), Patent registration no.
10-1181371 (09/04/2012)
Composition for diagnosis of M. Tuberculosis and Method for diagnosis using the same, Kim HJ, Shin SJ, Shin AR,
Patent application no. 10-2009-0097508 (10/14/2009), Patent registration no. 10-1135668 (04/04/2012)
Screening Methods for Diagnostic Markers for Mycobacterium abscessus Infection and Protein Antigens, Shin SJ, Kim HJ,
Shin AR, Oh JH, Patent application no. 10-2009-0034587 (04/21/2009), Patent registration no. 10-1140405 (04/19/2012)
Assay for Antibodies to Mycobacterium paratuberculosis, Shin SJ, Collins MT. Application No./Patent No.
07841886.0-1212 / 2084261 (08/19/2009, International patent, EU and USA)
MYCOBACTERIAL CULTURE SCREENING TEST FOR MYCOBACTERIUM AVIUM COMPLEX BACTERIA, Shin SJ,
Collins MT, 09723234.2-1223 / 2265955, (01/11/2011, International patent, EU and USA)
Method for Screening Makers for Diagnosis of Tuberculosis Phase and Protein Antigen, Cho SN, Shin SJ, Jeon BY,
Patent application no. 10-2008-0092934 (09/22/2008), Patent registration no. 10-1045666 (06/24/2011)
Novel Biomarkers For the Serodiagnosis of Crohn’s disease, Cho SN, Shin SJ, Kim HJ, Shin AR, Lee SS, Patent application
no. 10-2008-0062532 (06/30/2008), Patent registration no. 10-1094974 (12/09/2011)
Media for M. tuberculosis -growth enhancer and the Cultivation Method thereof, Cho SN, Shin SJ, Patent application no.
10-2008-0042027 (05/06/2008), Patent registration no. 10-1057053 (08/09/2011)

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