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HOME : 연구활동 : 박전한 교수님


Park PG, Jo SJ, Kim MJ, Kim HJ, Lee JH, Park CK, Kim H, Lee KY, Kim H, Park JH, Dong SM, Lee JM. Role of LOXL2
in the epithelial-mesenchymal transition and colorectal cancer metastasis. Oncotarget. 2017 May 25;8(46):80325-80335
Jo SJ, Park PG, Cha HR, Ahn SG, Kim MJ, Kim H, Koo JS, Jeong J, Park JH, Dong SM, Lee JM. Cellular inhibitor of
protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through
activation of the AKT signaling pathway. Oncotarget. 2017 Aug 12;8(45):78781-78795.
Yang CM, Yoon JC, Park JH, Lee JM. Hepatitis C virus impairs natural killer cell activity via viral serine protease NS3.
PLoS One. 2017 Apr 14;12(4):e0175793.
Park H, Ko SH, Lee JM, Park JH, Choi YH. Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer
Cells to Photodynamic Therapy. Yonsei Med J. 2016 Nov;57(6):1494-9.
Lee HG, Kim H, Son T, Jeong Y, Kim SU, Dong SM, Park YN, Lee JD, Lee JM, Park JH. Regulation of HK2 expression
through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma. Oncotarget.
2016 Jul 5;7(27):41798-41810.
Lee JD, Choi MA, Ro SW, Yang WI, Cho AE, Ju HL, Baek S, Chung SI, Kang WJ, Yun M, Park JH. Synergic
chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of
SIRT1. Eur J Cancer Prev. 2016 Jan;25(1):54-64.
Lee HG, Kim H, Kim EJ, Park PG, Dong SM, Choi TH, Kim H, Chong CR, Liu JO, Chen J, Ambinder RF, Hayward SD,
Park JH, Lee JM. Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose
gemcitabine-induced lytic activation. Oncotarget. 2015 Oct 13;6(31):31018-29.
Kim SU, Park JH, Kim HS, Lee JM, Lee HG, Kim H, Choi SH, Baek S, Kim BK, Park JY, Kim do Y, Ahn SH, Lee JD,
Han KH. Serum Dickkopf-1 as a Biomarker for the Diagnosis of Hepatocellular Carcinoma. Cancer Chemother Pharmacol.
2015 Aug;76(2):257-67.
Kim MN, Ro SW, Kim do Y, Kim da Y, Cho KJ, Park JH, Lim HY, Han KH. Efficacy of perifosine alone and in combination
with sorafenib in an HrasG12V plus shp53 transgenic mouse model of hepatocellular carcinoma. Cancer Chemother
Pharmacol. 2015 Aug;76(2):257-67.
Dong SM, Lee HG, Cho SG, Kwon SH, Yoon H, Kwon HJ, Lee JH, Kim H, Park PG, Kim H, Hayward SD, Park JH, Lee JM.
Hypermethylation of the interferon regulatory factor 5 promoter in Epstein-Barr virus-associated gastric carcinoma.
J Microbiol. 2015 Jan;53(1):70-6.
Kim HJ, Kim YJ, Yong DE, Lee K, Park JH, Lee JM, Yoon SS. Loop-mediated isothermal amplification of vanA gene
enables a rapid and naked-eye detection of vancomycin-resistant enterococci infection. J Microbiol Methods.
2014 Sep;104:61-6.
Kim BK, Choi SH, Ahn SH, Chung AR, Park YK, Han KH, Kim S, Kim HS, Park JH, Kim KS, Lee HS, Cho YS, Kim KH,
Ahn SH. Pre-S mutations of hepatitis B virus affect genome replication and expression of surface antigens. J Gastroenterol
Hepatol. 2014 Apr;29(4):843-50.
Park KH, Park B, Yoon DS, Kwon SH, Shin DM, Lee JW, Lee HG, Shim JH, Park JH, Lee JM. Zinc inhibits osteoclast
differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway. Cell Commun Signal, 2013, 11:74.Choi SH,
Kwon OJ, Park JY, Kim do Y, Ahn SH, Kim SU, Ro SW, Kim KS, Park JH, Kim S, Yun CO, Han KH. Inhibition of tumour
angiogenesis and growth by small hairpin HIF-1α and IL-8 in hepatocellular carcinoma. Liver Int. 2014 Apr;34(4):632-42.
Park KH, Park B, Yoon DS, Kwon SH, Shin DM, Lee JW, Lee HG, Shim JH, Park JH, Lee JM. Zinc inhibits osteoclast
differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway. Cell Commun Signal, 2013, 11:74.
Yoon JC, Lim JB, Park JH, Lee JM. Cell-to-Cell Contact with Hepatitis C Virus-Infected Cells Reduces Functional
Capacity of Natural Killer Cells. J Virol, 2011, 85(23):12557-12569.
Lee JM, Kim H, Noh SH, Lee WY, Kim SJ, Park JH. Expression of Epstein-Barr Virus Gene and Clonality of Infiltrated
T Lymphocytes in Epstein-Barr Virus-associated Gastric Carcinoma. Immune Netw, 2011, 11(1):50-58.
Lee JH, Han KH, Lee JM, Park JH, Kim HS. Impact of Hepatitis B Virus (HBV) X Gene Mutations on Hepatocellular
Carcinoma Development in Chronic HBV Infection. Clin Vaccine Immunol, 2011, 18(6):914-921.
Ahn KJ, Hwang HS, Park JH, Bang SH, Kang WJ, Yun M, Lee JD. Evaluation of the role of hexokinase type II in cellular
proliferation and apoptosis using human hepatocellular carcinoma cell lines. J Nucl Med, 2009, 50(9):1525-1532.
Ahn KJ, Kim J, Yun M, Park JH, Lee JD. Enzymatic properties of the N- and C-terminal halves of human hexokinase II.
BMB Rep, 2009, 42(6):350-355.
Kim JY, Chung KS, Park JH, Kwak YS, Lee BK. Characteristics of B-Cell-Specific Growth Substance Produced by
Bacillus licheniformis E1. J Microbiol Biotechnol, 2009, 19(1):55-64.
Kim JS, Ahn KJ, Kim JA, Kim HM, Lee JD, Lee JM, Kim SJ, Park JH. Role of reactive oxygen species-mediated
mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells - ROS-mediated cell death by
3-BrPA. J Bioenerg Biomembr. 2008, 40(6):607-618.
Um HR, Lim WC, Chae SY, Park S, Park JH, Cho H. Raf-1 and protein kinase B regulate cell survival through the
activation of NF-kappa B in hepatitis B virus X-expressing cells. Virus Res. 2007, 125(1):1-8.
Hwang HJ, Kwak YS, Yoon GA, Kang MH, Park JH, Lee BK, Kim SJ, Um SY, Kim YM. Combined effects of swim training
and ginseng supplementation on exercise performance time, ROS, lymphocyte proliferation, and DNA damage following
exhaustive exercise stress. Int J Vitam Nutr Res, 2007, 77(4):289-296.
Kim JS, Rho By, Lee TH, Lee JM, Kim SJ, Park JH. The interaction of hepatitis B virus X protein and protein phosphatase
type 2 C alpha and its effect on IL-6. Biochem Biophys Res Commun, 2006, 351(1):253-258.
Lee JD, Yang WI, Park YN, Kim KS, Choi JS, Yun M, Ko D, Kim TS, Cho AE, Kim HM, Han KH, Im SS, Ahn YH, Choi CW,
Park JH. Different glucose uptake and glycolytic mechanisms between hepatocellular carcinoma and intrahepatic
mass-forming cholangiocarcinoma with increased. J Nucl Med. 2005, 46(10):1753-1759.
Jeong J, Choi EC, Choi Y, Lee IK, Lee SA, Park JH, Ryu YH, Jung WH, Lee HD. Detection of micrometastasis in fixed
paraffin-embedded Sentinel Lymph Nodes of Breast cancer using RT-PCR. J Breast Cancer, 2005, 8(2):31-39.
Choi YH, Ko SH, Kim SJ, Lee WY, Park JH, Lee JM. Induction of cell death by photodynamic therapy with a new
synthetic photosensitizer DH-I-180-3 in undifferentiated and differentiated 3T3-L1 cells. Biochem Biophys Res Commun,
2005, 337(4):1059-1064.
Lee JM, Lee KH, Farrell CJ, Ling PD, Kempkes B, Park JH, Hayward SD. EBNA2 is required for protection of latently
Epstein-Barr virus-infected B cells against specific apoptotic stimuli. J Virol, 2004, 78(22):12694-12697.
Lee JD, Yun M, Lee JM, Choi Y, Choi YH, Kim JS, Kim SJ, Kim KS, Yang WI, Park YN, Han KH, Lee WJ, Yoo N, Lim SM,
Park JH. Analysis of gene expression profiles of hepatocellular carcinomas with regard to 18F-fluorodeoxyglucose uptake
pattern on positron emission tomography. Eur J Nucl Med Mol Imaging, 2004, 31(12):1621-1630.
Park SM, Ahn KJ, Jung HY, Park JH, Kim J. Effects of novel peptides derived from the acidic tail of synuclein (ATS) on the
aggregation and stability of fusion proteins. Protein Eng Des Sel, 2004, 17(3):251-260.
Kim JS, Lee JM, Chwae YJ, Kim YH, Lee JH, Kim K, Lee TH, Kim SJ, Park JH. Cisplatin-induced apoptosis in Hep3B
cells: mitochondria-dependent and independent pathways. Biochem Pharmacol, 2004, 67(8):1459-1468.
Choi YH, Kim HI, Seong JK, Yu DY, Cho H, Lee MO, Lee JM, Ahn YH, Kim SJ, Park JH. Hepatitis B virus X protein
modulates peroxisome proliferator-activated receptor γ through protein-protein interaction. FEBS Letters,
2004, 557(1-3):73-80.
Kim HR, Park HJ, Park JH, Kim SJ, Kim K, Kim J. Characteristics of the killing mechanism of human natural killer cells
against hepatocellular carcinoma cell lines HepG2 and Hep3B. Cancer Immunol Immunother, 2004, 53(5):461-470.
Kwak YS, Park JH, Kim SJ, Jang YS, Lee BK. The Effects of Swimming Training on Lymphocyte Proliferation and ROS
Production in Spleen Lymphocytes of BALB/c Mice. Immune Netw, 2002, 2(2):96-101.
Heo YS, Ryu JM, Park SM, Park JH, Lee HC, Hwang KY, Kim J. Structural basis for inhibition of protein tyrosine
phosphatases by Keggin compounds phosphomolybdate and phosphotungstate. Exp Mol Med, 2002, 34(3):211-223.
Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH. Human hepatocellular carcinoma cells
resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Exp Mol Med, 2002, 34(2):114-122.
Lee MO, Choi YH, Shin EC, Kang HJ, Kim YM, Jeong SY, Seong JK, Yu DY, Cho H, Park JH, Kim SJ. Hepatitis B virus X
protein induced expression of interleukin 18: a potential mechanism for liver injury caused by hepatitis B virus (HBV)
infection. J Hepatol, 2002, 37(3):380-386.
Park SM, Jung HY, Kim TD, Park JH, Yang CH, Kim J. Distinct roles of the N-terminal-binding domain and the C-terminal-
solubilizing domain of alpha-synuclein, a molecular chaperone. J Biol Chem, 2002, 277(32):28512-28520.
Shin EC, Choi YH, Kim JS, Kim SJ, Park JH. Expression patterns of cytokines and chemokines genes in human hepatoma
cells. Yonsei Med J, 2002, 43(5):657-664.
Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH. Human hepatocellular carcinoma cells
resist to TRAIL-induced apoptosis and the resistance is abolished by cisplatin. Exp Mol Med, 2002, 34(2):114-122.
Lee JD, Yang WI, Lee MG, Ryu YH, Park JH, Shin KH, Kim GE, Suh CO, Seong JS, Han BH, Choi CW, Kim EH, Kim KH,
Park KB. Effective local control of malignant melanoma by intratumoral injection of a beta-emitting radionucleotide.
Eur J Nucl Med Mol Imaging, 2002, 29(2):221-230.
Lee SJ, Choi YJ, You YS, Ko HJ, Lee JH, Lee SC, Park JH, Kwon OW. Polymerase Chain Reaction in the Diagnosis of
Infectious Endophthalmitis. J Korean Ophthalmol Soc, 2001, 42(4): Endpage 600-606.
Shin EC, Ahn JM, Kim CH, Choi Y, Ahn YS, Kim H, Kim SJ, Park JH. IFN-gamma induces cell death in human hepatoma
cells through a TRAIL/death receptor-mediated apoptotic pathway. Int J Cancer, 2001, 93(2):262-268.
Shin EC, Shin WC, Choi Y, Kim H, Park JH, Kim SJ. Hepatitis B virus X protein induced expression of the Nur77 Gene.
Cancer Immunol Immunother, 2001, 50(1):23-30.
Shin EC, Shin WC, Choi Y, Kim H, Park JH, Kim SJ. Effect of interferon-gamma on the susceptibility to Fas (CD95/APO-1)
mediated cell death in human hepatoma cells. Cancer Immunol Immunother, 2001, 50(1):23-30.
Kim HJ, Shin EC, Yoo NJ, Park JH, Kim SJ, Kang ES, Jahng JS. Apoptosis of chondro cytes and its regulation in
pathogenesis of osteoarthritis. J Korean Rheum Assoc, 2001, 8(2):104- 117.
Baek MJ, Kang H, Kim SE, Park JH, Lee JS, Paik YK, Kim H. Expression of hMLH1 is inactivated in the gastric adenomas
with enhanced microsatellite instability. Br J Cancer, 2001, 85(8):1147-1152.
Shin EC, Ahn JM, Kim CH, Choi Y, Ahn YS, Kim H, Kim SJ, Park JH. IFN-γ induces cells death in human hepatoma cells
through a TRAIL/death receptor-mediated apoptotic pathway. Int J Cancer, 2001, 93(2):262-268.
Kim WH, Yeo M, Kim MS, Chun SB, Shin EC, Park JH, Park IS. Role of caspase-3 in apoptosis of colon cancer cells
induced by nonsteroid anti-inflammatory drugs. Int J Colorectal Dis, 2000, 15(2):105-111.
Chang KH, Kim JM, Yoo NC, Kim WH, Park JH, Choi IH, Kim HS, Lee KW, Song YG, Hong SK, Kim HY. Restoration of
P-glycoprotein function is involved in the increase of Natural Killer activity with exogenous interleukin-15 in human
immunodeficiency virus-infected individuals. Yonsei Med J, 2000, 41(5):600-606.
Jin M, Piao Z, Kim NG, Park C, Shin EC, Park JH, Jung HJ, Kim CG, Kim H. p16 is a major inactivation target in
hepatocellular carcinoma. Cancer, 2000, 89(1):60-68.
Shin EC, Cho SE, Lee DK, Hur MW, Paik SR, Park JH, Kim J. Expression patterns of alpha-synuclein in human
hematopoietic cells and in Drosophila at different developmental stages. Mol Cells, 2000, 10(1):65-70.
Kwon D, Chwae YJ, Choi IH, Park JH, Kim SJ, Kim J. Diversity of the p70 killer inhibitory receptor (KIR3D) family members
in a single individual. Mol Cells, 2000, 10(1):54-60
Lee MO, Han SY, Jiang S, Park JH, Kim SJ. Differential effects of retinoids on the growth and apoptosis in human colon
cancer cell lines associated with the induction of RARβ. Biochem Pharmacol, 2000, 59(5):485~496.
Lee TJ, Kim SJ, Park JH. Influence of the sequence variations of the HLA-DR promoters derived from human melanoma
cell lines on nuclear protein binding and promoter activity. Yonsei Med J, 2000, 41(5):593-599.

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